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[bing.com](https://www.bing.com/search?q=legal+professional)The value of creating extensive, tissue-particular maps of protein lysine acetylation sites is further underscored by the numerous function of posttranslational modifications within the evolution and phenotypic composition of vertebrates, as indicated by the significant selective strain gene regulatory elements close to posttranslational-modifying enzymes have come underneath in placental animals ( Lowe et al., 2011 ). Right here, we combined an efficient technique for protein extraction from tissue samples with lysine-acetylated peptide immunoprecipitation and excessive-accuracy tandem mass spectrometric (MS/MS) measurements, which allowed us to generate an atlas of lysine acetylation sites in sixteen totally different rat tissues. |